Title: Nonlinear Mixed Effects Models in Population PK/PD, Estimation
Routines
Description: Fit and compare nonlinear mixed-effects models in
differential equations with flexible dosing information commonly seen
in pharmacokinetics and pharmacodynamics (Almquist, Leander, and
Jirstrand 2015 <doi:10.1007/s10928-015-9409-1>). Differential equation
solving is by compiled C code provided in the 'rxode2' package (Wang,
Hallow, and James 2015 <doi:10.1002/psp4.12052>).
Author: Matthew Fidler [aut, cre] ,
Yuan Xiong [aut],
Rik Schoemaker [aut] ,
Justin Wilkins [aut] ,
Wenping Wang [aut],
Robert Leary [ctb],
Mason McComb [ctb] ,
Vipul Mann [aut],
Mirjam Trame [ctb],
Mahmoud Abdelwahab [ctb],
Teun Post [ctb],
Richard Hooijmai [...truncated...]
Maintainer: Matthew Fidler <matthew.fidler@gmail.com>
Diff between nlmixr2est versions 3.0.1 dated 2024-10-22 and 3.0.2 dated 2024-11-23
nlmixr2est-3.0.1/nlmixr2est/R/preProcessModel.R |only nlmixr2est-3.0.2/nlmixr2est/DESCRIPTION | 6 - nlmixr2est-3.0.2/nlmixr2est/MD5 | 46 ++++++---- nlmixr2est-3.0.2/nlmixr2est/NAMESPACE | 6 + nlmixr2est-3.0.2/nlmixr2est/NEWS.md | 12 ++ nlmixr2est-3.0.2/nlmixr2est/R/bobyqa.R | 4 nlmixr2est-3.0.2/nlmixr2est/R/hook.R |only nlmixr2est-3.0.2/nlmixr2est/R/lbfgsb3c.R | 3 nlmixr2est-3.0.2/nlmixr2est/R/n1qn1.R | 3 nlmixr2est-3.0.2/nlmixr2est/R/newuoa.R | 3 nlmixr2est-3.0.2/nlmixr2est/R/nlm.R | 3 nlmixr2est-3.0.2/nlmixr2est/R/nlminb.R | 4 nlmixr2est-3.0.2/nlmixr2est/R/nlmixr2.R | 9 + nlmixr2est-3.0.2/nlmixr2est/R/nlmixr2_md5.R | 2 nlmixr2est-3.0.2/nlmixr2est/R/nls.R | 2 nlmixr2est-3.0.2/nlmixr2est/R/optim.R | 4 nlmixr2est-3.0.2/nlmixr2est/R/preProcessDataUi.R |only nlmixr2est-3.0.2/nlmixr2est/R/preProcessLiteralFix.R |only nlmixr2est-3.0.2/nlmixr2est/R/preProcessZeroOmega.R |only nlmixr2est-3.0.2/nlmixr2est/R/uobyqa.R | 3 nlmixr2est-3.0.2/nlmixr2est/inst/tools/workaround.R | 22 +++- nlmixr2est-3.0.2/nlmixr2est/man/dot-nlmixrPreprocessLiteralFix.Rd |only nlmixr2est-3.0.2/nlmixr2est/man/dot-preProcessDataUi.Rd |only nlmixr2est-3.0.2/nlmixr2est/man/dot-preProcessZeroOmega.Rd |only nlmixr2est-3.0.2/nlmixr2est/man/figures/README-example-1.png |binary nlmixr2est-3.0.2/nlmixr2est/man/preProcessHooks.Rd |only nlmixr2est-3.0.2/nlmixr2est/man/preProcessHooksAdd.Rd |only nlmixr2est-3.0.2/nlmixr2est/man/preProcessHooksRm.Rd |only nlmixr2est-3.0.2/nlmixr2est/src/inner.cpp | 8 + nlmixr2est-3.0.2/nlmixr2est/tests/testthat/test-omega-boundary.R |only 30 files changed, 96 insertions(+), 44 deletions(-)